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Sulfonation of the Resolving Cysteine in Human Peroxiredoxin 1: A Comprehensive Analysis by Mass Spectrometry

Peroxiredoxin 1 (Prx1) is an essential peroxidase that reduces cellular peroxides. It holds 2 indispensable cysteines for its activity: a peroxidatic cysteine (C(P)) for peroxide reduction and a resolving cysteine (C(R)) for C(P) regeneration. C(P) can be readily sulfonated to C(P)–SO(3)H by protrac...

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Wu, Changgong, Dai, Huacheng, Yan, Lin, cui, Chuanlong, Liu, Tong, Chen, Tong, Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564515/
https://ncbi.nlm.nih.gov/pubmed/28450148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2017.04.341
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