Downregulation of BRD4 inhibits gallbladder cancer proliferation and metastasis and induces apoptosis via PI3K/AKT pathway

Bromodomain containing protein 4 (BRD4) has been demonstrated to play a critical role in tumor progression. However, the expression and function of BRD4 in gallbladder cancer (GBC) are still unknown. In this study, we report that BRD4 expression level was significantly upregulated in GBC tissues and...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Hao, Jiaqi, Yang, Ziyi, Wang, Lei, Zhang, Yijian, Shu, Yijun, Jiang, Lin, Hu, Yunping, Lv, Wenjie, Dong, Ping, Liu, Yingbin
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564407/
https://ncbi.nlm.nih.gov/pubmed/28766687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4081
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