Population Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) in Preterm and Term Neonates: Model Development and External Evaluation

OBJECTIVES: The aims of this study were to develop a population pharmacokinetic model for intravenous paracetamol in preterm and term neonates and to assess the generalizability of the model by testing its predictive performance in an external dataset. METHODS: Nonlinear mixed-effects models were co...

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Detaylı Bibliyografya
Yayımlandı:Clin Pharmacokinet
Asıl Yazarlar: Cook, Sarah F., Roberts, Jessica K., Samiee-Zafarghandy, Samira, Stockmann, Chris, King, Amber D., Deutsch, Nina, Williams, Elaine F., Allegaert, Karel, Wilkins, Diana G., Sherwin, Catherine M. T., van den Anker, John N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564323/
https://ncbi.nlm.nih.gov/pubmed/26201306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-015-0301-3
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