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Protein Pathway Activation Mapping of Brain Metastasis from Lung and Breast Cancers Reveals Organ Type Specific Drug Target Activation

Brain metastases are the most common fatal complication of systemic cancer, especially of lung (40–50%) and breast (20–30%) cancers. In this era of personalized therapy, there is a critical need to uncover the signaling architecture of brain metastases; however, little is known about what signaling...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Improta, Giuseppina, Zupa, Angela, Fillmore, Helen, Deng, Jianghong, Aieta, Michele, Musto, Pellegrino, Liotta, Lance A., Broaddus, William, Petricoin, Emanuel F., Wulfkuhle, Julia D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564317/
https://ncbi.nlm.nih.gov/pubmed/21574647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200065t
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