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CaMKIIγ-mediated inactivation of the Kin I kinesin MCAK is essential for bipolar spindle formation
MCAK, a member of the kinesin-13 family, is a microtubule (MT) depolymerase that is necessary to ensure proper kinetochore MT attachment during spindle formation. Regulation of MCAK activity and localization is controlled in part by Aurora B kinase at the centromere. Here we analyzed human cells dep...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC556404/ https://ncbi.nlm.nih.gov/pubmed/15775983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600601 |
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