NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy

Although tumor-associated macrophages have been extensively studied in the control of response to radiotherapy, the molecular mechanisms involved in the ionizing radiation-mediated activation of macrophages remain elusive. Here we show that ionizing radiation induces the expression of interferon reg...

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Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Wu, Qiuji, Allouch, Awatef, Paoletti, Audrey, Leteur, Celine, Mirjolet, Celine, Martins, Isabelle, Voisin, Laurent, Law, Frédéric, Dakhli, Haithem, Mintet, Elodie, Thoreau, Maxime, Muradova, Zeinaf, Gauthier, Mélanie, Caron, Olivier, Milliat, Fabien, Ojcius, David M, Rosselli, Filippo, Solary, Eric, Modjtahedi, Nazanine, Deutsch, Eric, Perfettini, Jean-Luc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563995/
https://ncbi.nlm.nih.gov/pubmed/28574504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.91
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