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Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness

Radiation therapy is one of the cornerstones of cancer treatment. In tumor cells, exposure to ionizing radiation (IR) provokes DNA damages that trigger various forms of cell death such as apoptosis, necrosis, autophagic cell death, and mitotic catastrophe. IR can also induce cellular senescence that...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Wu, Qiuji, Allouch, Awatef, Martins, Isabelle, Brenner, Catherine, Modjtahedi, Nazanine, Deutsch, Eric, Perfettini, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445662/
https://ncbi.nlm.nih.gov/pubmed/28603525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00613
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