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Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness

Radiation therapy is one of the cornerstones of cancer treatment. In tumor cells, exposure to ionizing radiation (IR) provokes DNA damages that trigger various forms of cell death such as apoptosis, necrosis, autophagic cell death, and mitotic catastrophe. IR can also induce cellular senescence that...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Wu, Qiuji, Allouch, Awatef, Martins, Isabelle, Brenner, Catherine, Modjtahedi, Nazanine, Deutsch, Eric, Perfettini, Jean-Luc
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5445662/
https://ncbi.nlm.nih.gov/pubmed/28603525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00613
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