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BCL-2 family: integrating stress responses at the ER to control cell demise

In the last decade, the endoplasmic reticulum (ER) has emerged as a central organelle regulating the core mitochondrial apoptosis pathway. At the ER membrane, a variety of stress signals are integrated toward determining cell fate, involving a complex cross talk between key homeostatic pathways incl...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Pihán, Philippe, Carreras-Sureda, Amado, Hetz, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563989/
https://ncbi.nlm.nih.gov/pubmed/28622296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.82
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