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SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death

Nuclear receptor NR4A1 has been implicated as a key regulator in a wide range of pathophysiological responses. As an immediate early response gene, NR4A1 can be rapidly and potently induced by a variety of stimuli. Its induction is followed by its rapid degradation, but the mechanism by which NR4A1...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Zhang, Long, Xie, Feng, Zhang, Juan, Dijke, Peter ten, Zhou, Fangfang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563982/
https://ncbi.nlm.nih.gov/pubmed/28622293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.29
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