Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice

The imbalance between ß-amyloid (Aß) generation and clearance plays a fundamental role in the pathogenesis of Alzheimer’s disease (AD). The sporadic form of AD is characterized by an overall impairment in Aß clearance. Immunotherapy targeting Aß clearance is believed to be a promising approach and i...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Wang, He-Cheng, Zhang, Tao, Kuerban, Bolati, Jin, Ying-Lan, Le, Weidong, Hara, Hideo, Fan, Dong-Sheng, Wang, Yan-Jiang, Tabira, Takeshi, Chui, De-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563717/
https://ncbi.nlm.nih.gov/pubmed/26254061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-015-1546-4
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