Autophagy is involved in oral rAAV/Aβ vaccine-induced Aβ clearance in APP/PS1 transgenic mice

The imbalance between ß-amyloid (Aß) generation and clearance plays a fundamental role in the pathogenesis of Alzheimer’s disease (AD). The sporadic form of AD is characterized by an overall impairment in Aß clearance. Immunotherapy targeting Aß clearance is believed to be a promising approach and i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Neurosci Bull
Autori principali: Wang, He-Cheng, Zhang, Tao, Kuerban, Bolati, Jin, Ying-Lan, Le, Weidong, Hara, Hideo, Fan, Dong-Sheng, Wang, Yan-Jiang, Tabira, Takeshi, Chui, De-Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2015
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563717/
https://ncbi.nlm.nih.gov/pubmed/26254061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-015-1546-4
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi