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IGFBP-1 hyperphosphorylation in response to leucine deprivation is mediated by the AAR pathway
Insulin-like growth factor-1 (IGF-I) is the key regulator of fetal growth. IGF-I bioavailability is markedly diminished by IGF binding protein-1 (IGFBP-1) phosphorylation. Leucine deprivation strongly induces IGFBP-1hyperphosphorylation, and plays an important role in fetal growth restriction (FGR)....
Sparad:
| I publikationen: | Mol Cell Endocrinol |
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| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563670/ https://ncbi.nlm.nih.gov/pubmed/25957086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.04.031 |
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