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Establishment of NF-κB sensing and IL-4 secreting mesenchymal stromal cells as an “on-demand” drug delivery system to modulate inflammation
Chronic inflammation is associated with upregulation of the transcription factor NF-κB and excessive inflammatory cytokine secretion by M1 macrophages. The anti-inflammatory cytokine IL-4 converts pro-inflammatory M1 macrophages into an anti-inflammatory and tissue regenerative M2 phenotype, thus re...
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| Pubblicato in: | Cytotherapy |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563472/ https://ncbi.nlm.nih.gov/pubmed/28739167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcyt.2017.06.008 |
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