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The structure of RbmB from Streptomyces ribosidificus, an aminotransferase involved in the biosynthesis of ribostamycin

Aminoglycoside antibiotics represent a classical group of antimicrobials first discovered in the 1940s. Due to their ototoxic and nephrotoxic side effects, they are typically only used against Gram negative bacteria which have become resistant to other therapeutics. One family of aminoglycosides inc...

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Veröffentlicht in:Protein Sci
Hauptverfasser: Zachman‐Brockmeyer, Trevor R., Thoden, James B., Holden, Hazel M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563144/
https://ncbi.nlm.nih.gov/pubmed/28685903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3221
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