Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit

Amyotrophic lateral sclerosis (ALS) is a devastating disorder of the central nervous system in middle and old age that leads to progressive loss of spinal motoneurons. Transgenic mice overexpressing mutated human Cu(2+)/Zn(2+) superoxide dismutase 1 (SOD1) reproduce clinical features of the familial...

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Detalhes bibliográficos
Main Authors: Kuner, Rohini, Groom, Anthony J., Bresink, Iris, Kornau, Hans-Christian, Stefovska, Vanya, Müller, Gerald, Hartmann, Bettina, Tschauner, Karsten, Waibel, Stefan, Ludolph, Albert C., Ikonomidou, Chrysanthy, Seeburg, Peter H., Turski, Lechoslaw
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556301/
https://ncbi.nlm.nih.gov/pubmed/15827116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501316102
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