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Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice

Chronic inflammation can be a major driver of the failure of a variety of organs, including chronic kidney disease (CKD). The NLR family pyrin domain-containing 3 (NLRP3) inflammasome has been shown to play a pivotal role in inflammation in a mouse kidney disease model. Nuclear factor erythroid 2-re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sogawa, Yuji, Nagasu, Hajime, Iwase, Shigeki, Ihoriya, Chieko, Itano, Seiji, Uchida, Atsushi, Kidokoro, Kengo, Taniguchi, Shun’ichiro, Takahashi, Masafumi, Satoh, Minoru, Sasaki, Tamaki, Suzuki, Takafumi, Yamamoto, Masayuki, Horng, Tiffany, Kashihara, Naoki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562821/
https://ncbi.nlm.nih.gov/pubmed/28821730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08054-2
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