N-glycosylation Triggers a Dual Selection Pressure in Eukaryotic Secretory Proteins

Nearly one third of the eukaryotic proteome traverses the secretory pathway and most of these proteins are N-glycosylated in the lumen of the endoplasmic reticulum. N-glycans fulfill multiple structural and biological functions, and are crucial for productive folding of many glycoproteins. N-glycosy...

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Publicat a:Sci Rep
Autors principals: Medus, Máximo Lopez, Gomez, Gabriela E., Zacchi, Lucía F., Couto, Paula M., Labriola, Carlos A., Labanda, María S., Bielsa, Rodrigo Corti, Clérico, Eugenia M., Schulz, Benjamin L., Caramelo, Julio J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562741/
https://ncbi.nlm.nih.gov/pubmed/28821844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09173-6
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