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Protein Fibrillation Lag Times During Kinetic Inhibition
Protein aggregation is linked to more than 30 human pathologies, including Alzheimer’s and Parkinson’s diseases. Since small oligomers that form at the beginning of the fibrillation process probably are the most toxic elements, therapeutic strategies involving fibril fragmentation could be detriment...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4129507/ https://ncbi.nlm.nih.gov/pubmed/25099810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.029 |
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