Protein Fibrillation Lag Times During Kinetic Inhibition

Protein aggregation is linked to more than 30 human pathologies, including Alzheimer’s and Parkinson’s diseases. Since small oligomers that form at the beginning of the fibrillation process probably are the most toxic elements, therapeutic strategies involving fibril fragmentation could be detriment...

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Detaylı Bibliyografya
Asıl Yazarlar: Pagano, Rodrigo S., López Medus, Máximo, Gómez, Gabriela E., Couto, Paula M., Labanda, María S., Landolfo, Lucas, D’Alessio, Cecilia, Caramelo, Julio J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Biophysical Society 2014
Konular:
Proteins and Nucleic Acids
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129507/
https://ncbi.nlm.nih.gov/pubmed/25099810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.06.029
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