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Structural basis for the broad substrate specificity of the human tyrosylprotein sulfotransferase-1

Tyrosylprotein sulfotransferases (TPSTs) are enzymes that catalyze post-translational tyrosine sulfation of proteins. In humans, there are only two TPST isoforms, designated TPST1 and TPST2. In a previous study, we reported the crystal structure of TPST2, which revealed the catalytic mechanism of th...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tanaka, Shinnosuke, Nishiyori, Toshiaki, Kojo, Hidetaka, Otsubo, Reo, Tsuruta, Moe, Kurogi, Katsuhisa, Liu, Ming-Cheh, Suiko, Masahito, Sakakibara, Yoichi, Kakuta, Yoshimitsu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562738/
https://ncbi.nlm.nih.gov/pubmed/28821720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07141-8
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