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Sulfation of 6-hydroxymelatonin, N-acetylserotonin and 4-hydroxyramelteon by the human cytosolic sulfotransferases (SULTs)

1. The present study aimed to investigate the involvement of sulfation in the metabolism of 6-hydroxymelatonin (6-OH-Mel), N-acetylserotonin (NAS) and 4-hydroxyramelteon (4-OH-Ram), and to identify and characterize the human cytosolic sulfotransferases (SULTs) capable of sulfating these drug compoun...

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Détails bibliographiques
Publié dans:Xenobiotica
Auteurs principaux: Luo, Lijun, Zhou, Chunyang, Kurogi, Katsuhisa, Sakakibara, Yoichi, Suiko, Masahito, Liu, Ming-Cheh
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123980/
https://ncbi.nlm.nih.gov/pubmed/26577053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2015.1107656
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