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Tau-induced neurodegeneration: mechanisms and targets

The accumulation of hyperphosphorylated tau is a common feature of several dementias. Tau is one of the brain microtubule-associated proteins. Here we discuss tau’s functions in microtubule assembly and stabilization and with regard to its interactions with other proteins. We describe and analyze im...

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Détails bibliographiques
Publié dans:Neurosci Bull
Auteurs principaux: Beharry, Cindy, Cohen, Leah S., Di, Jing, Ibrahim, Kawsar, Briffa-Mirabella, Susan, Alonso, Alejandra del C.
Format: Artigo
Langue:Inglês
Publié: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562659/
https://ncbi.nlm.nih.gov/pubmed/24733656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1414-z
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