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Effects of metal ions on the structure and activity of a human anti-cyclin D1 single-chain variable fragment AD5

Cyclin D1 has become a potential target for anti-tumor therapy. Recently, a novel human anti-cyclin D1 single-chain variable fragment (AD5) was identified, which demonstrated specific binding activity to cyclin D1 and exhibited anti-tumor effects. However, the detailed characteristics of AD5 remain...

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Vydáno v:Mol Med Rep
Hlavní autoři: Yang, Ning, Yao, Nannan, Liao, Xiangzhi, Xie, Xiaona, Wu, Yan, Fan, Chuanxi, Zhao, Jialiang, Li, Guiying
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561975/
https://ncbi.nlm.nih.gov/pubmed/28627625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6756
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