Locomotor activity and anxiety status, but not spatial working memory, are affected in mice after brief exposure to cuprizone

Chronic long-term exposure to cuprizone causes severe brain demyelination in mice, which leads to changes in locomotion, working memory and anxiety. These findings suggest the importance of intact myelin for these behaviors. This study aimed to investigate the possible behavioral changes in mice wit...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Zhang, Handi, Zhang, Yanbo, Xu, Haiyun, Wang, Lingyan, Zhao, Jinsong, Wang, Junhui, Zhang, Zhijun, Tan, Qingrong, Kong, Jiming, Huang, Qingjun, Li, Xin-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561963/
https://ncbi.nlm.nih.gov/pubmed/23990221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1369-0
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