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Locomotor activity and anxiety status, but not spatial working memory, are affected in mice after brief exposure to cuprizone

Chronic long-term exposure to cuprizone causes severe brain demyelination in mice, which leads to changes in locomotion, working memory and anxiety. These findings suggest the importance of intact myelin for these behaviors. This study aimed to investigate the possible behavioral changes in mice wit...

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Dettagli Bibliografici
Pubblicato in:Neurosci Bull
Autori principali: Zhang, Handi, Zhang, Yanbo, Xu, Haiyun, Wang, Lingyan, Zhao, Jinsong, Wang, Junhui, Zhang, Zhijun, Tan, Qingrong, Kong, Jiming, Huang, Qingjun, Li, Xin-Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561963/
https://ncbi.nlm.nih.gov/pubmed/23990221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1369-0
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