Locomotor activity and anxiety status, but not spatial working memory, are affected in mice after brief exposure to cuprizone

Chronic long-term exposure to cuprizone causes severe brain demyelination in mice, which leads to changes in locomotion, working memory and anxiety. These findings suggest the importance of intact myelin for these behaviors. This study aimed to investigate the possible behavioral changes in mice wit...

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Dades bibliogràfiques
Publicat a:Neurosci Bull
Autors principals: Zhang, Handi, Zhang, Yanbo, Xu, Haiyun, Wang, Lingyan, Zhao, Jinsong, Wang, Junhui, Zhang, Zhijun, Tan, Qingrong, Kong, Jiming, Huang, Qingjun, Li, Xin-Min
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2013
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561963/
https://ncbi.nlm.nih.gov/pubmed/23990221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-013-1369-0
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