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Stratified Polygenic Risk Prediction Model with Application to CAGI Bipolar Disorder Sequencing Data

Genetic data consists of a wide range of marker types, including common, low frequency, and rare variants. Multiple genetic markers and their interactions play central roles in the heritability of complex disease. In this study, we propose an algorithm that uses a stratified variable selection desig...

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Detalhes bibliográficos
Publicado no:Hum Mutat
Main Authors: Wang, Maggie Haitian, Chang, Billy, Sun, Rui, Hu, Inchi, Xia, Xiaoxuan, Wu, William Ka Kei, Chong, Ka Chun, Zee, Benny Chung-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561515/
https://ncbi.nlm.nih.gov/pubmed/28419606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.23229
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