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Incorporating methylation genome information improves prediction accuracy for drug treatment responses

BACKGROUND: An accumulation of evidence has revealed the important role of epigenetic factors in explaining the etiopathogenesis of human diseases. Several empirical studies have successfully incorporated methylation data into models for disease prediction. However, it is still a challenge to integr...

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Podrobná bibliografie
Vydáno v:BMC Genet
Hlavní autoři: Xia, Xiaoxuan, Weng, Haoyi, Men, Ruoting, Sun, Rui, Zee, Benny Chung Ying, Chong, Ka Chun, Wang, Maggie Haitian
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157255/
https://ncbi.nlm.nih.gov/pubmed/30255773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12863-018-0644-5
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