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Propofol Affects Neurodegeneration and Neurogenesis by Regulation of Autophagy via Effects on Intracellular Calcium Homeostasis

BACKGROUND: In human cortical neural progenitor cells, we investigated the effects of propofol on calcium homeostasis in both the ryanodine and inositol 1, 4, 5-trisphosphate calcium release channels. We also studied propofol-mediated effects on autophagy, cell survival and neuro- and gliogenesis. M...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Qiao, Hui, Li, Yun, Xu, Zhendong, Li, Wenxian, Fu, Zhijian, Wang, Yuezhi, King, Alexander, Wei, Huafeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561483/
https://ncbi.nlm.nih.gov/pubmed/28614084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000001730
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