Zinc inhibition of γ-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission

γ-Aminobutyric acid (GABA) transporters (GATs) play an important role in inhibitory neurotransmission by clearing synaptically released GABA and by maintaining low resting levels of GABA in synaptic and extrasynaptic regions. In certain brain regions, vesicular zinc is colocalized and coreleased wit...

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Bibliographic Details
Main Authors: Cohen-Kfir, Einav, Lee, William, Eskandari, Sepehr, Nelson, Nathan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC556128/
https://ncbi.nlm.nih.gov/pubmed/15829583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501431102
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