Inhibitors of the γ-Aminobutyric Acid Transporter 1 (GAT1) Do Not Reveal a Channel Mode of Conduction

We expressed the γ-aminobutyric acid (GABA) transporter GAT1 (SLC6A1) in Xenopus laevis oocytes and performed GABA uptake experiments under voltage clamp at different membrane potentials as well as in the presence of the specific GAT1 inhibitors SKF-89976A and NO-711. In the absence of the inhibitor...

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Bibliographic Details
Main Authors: Matthews, Edward, Rahnama-Vaghef, Ali, Eskandari, Sepehr
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764797/
https://ncbi.nlm.nih.gov/pubmed/19622377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.07.005
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