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Inhibitors of the γ-Aminobutyric Acid Transporter 1 (GAT1) Do Not Reveal a Channel Mode of Conduction

We expressed the γ-aminobutyric acid (GABA) transporter GAT1 (SLC6A1) in Xenopus laevis oocytes and performed GABA uptake experiments under voltage clamp at different membrane potentials as well as in the presence of the specific GAT1 inhibitors SKF-89976A and NO-711. In the absence of the inhibitor...

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Bibliografske podrobnosti
Main Authors: Matthews, Edward, Rahnama-Vaghef, Ali, Eskandari, Sepehr
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764797/
https://ncbi.nlm.nih.gov/pubmed/19622377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2009.07.005
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