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DNA repair proteins affect the lifecycle of herpes simplex virus 1

We report that herpes simplex virus 1 (HSV-1) infection can activate and exploit a cellular DNA damage response that aids viral replication in nonneuronal cells. Early in HSV-1 infection, several members of the cellular DNA damage-sensing machinery are activated and accumulate at sites of viral DNA...

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Библиографические подробности
Главные авторы: Lilley, Caroline E., Carson, Christian T., Muotri, Alysson R., Gage, Fred H., Weitzman, Matthew D.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC556126/
https://ncbi.nlm.nih.gov/pubmed/15824307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501916102
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