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Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems

Metformin is an antidiabetic drug, which inhibits mitochondrial respiratory-chain-complex I and thereby seems to affect the cellular metabolism in many ways. It is also used for the treatment of the polycystic ovary syndrome (PCOS), the most common endocrine disorder in women. In addition, metformin...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Udhane, Sameer S., Legeza, Balazs, Marti, Nesa, Hertig, Damian, Diserens, Gaëlle, Nuoffer, Jean-Marc, Vermathen, Peter, Flück, Christa E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561186/
https://ncbi.nlm.nih.gov/pubmed/28819133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09189-y
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