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Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents

Among the enzymes involved in the post-translational modification of Ras, isoprenyl carboxyl methyltransferase (ICMT) has been explored by a number of researchers as a significant enzyme controlling the activation of Ras. Indeed, inhibition of ICMT exhibited promising anti-cancer activity against va...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Amino Acids
Main Authors: Yang, Woo Seok, Yeo, Seung-Gu, Yang, Sungjae, Kim, Kyung-Hee, Yoo, Byong Chul, Cho, Jae Youl
Format: Artigo
Jezik:Inglês
Izdano: Springer Vienna 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561173/
https://ncbi.nlm.nih.gov/pubmed/28631011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-017-2454-x
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