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Decoding disease-causing mechanisms of missense mutations from supramolecular structures
The inheritance modes of pathogenic missense mutations are known to be highly associated with protein structures; recessive mutations are mainly observed in the buried region of protein structures, whereas dominant mutations are significantly enriched in the interfaces of molecular interactions. How...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561164/ https://ncbi.nlm.nih.gov/pubmed/28819267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08902-1 |
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