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Periostin-binding DNA aptamer treatment attenuates renal fibrosis under diabetic conditions
Diabetic nephropathy, the major cause of chronic kidney disease, is associated with progressive renal fibrosis. Recently, accumulation of periostin, an extracellular matrix protein, was shown to augment renal fibrosis. Aptamers have higher binding affinities without developing the common side effect...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561139/ https://ncbi.nlm.nih.gov/pubmed/28819200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09238-6 |
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