Periostin-Binding DNA Aptamer Treatment Ameliorates Peritoneal Dialysis-Induced Peritoneal Fibrosis

Peritoneal fibrosis is a major complication in peritoneal dialysis (PD) patients, which leads to dialysis discontinuation. Periostin, increased by transforming growth factor β1 (TGF-β1) stimulation, induces the expression of extracellular matrix (ECM) genes. Aberrant periostin expression has been de...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Nam, Bo Young, Park, Jung Tak, Kwon, Young Eun, Lee, Jung Pyo, Jung, Jong Ha, Kim, Youndong, Kim, Seonghun, Park, Jimin, Um, Jae Eun, Wu, Meiyan, Han, Seung Hyeok, Yoo, Tae-Hyun, Kang, Shin-Wook
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436072/
https://ncbi.nlm.nih.gov/pubmed/28624215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.05.001
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