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Investigation of Seizure-Susceptibility in a Drosophila melanogaster Model of Human Epilepsy with Optogenetic Stimulation

We examined seizure-susceptibility in a Drosophila model of human epilepsy using optogenetic stimulation of ReaChR (red-activatable channelrhodopsin). Photostimulation of the seizure-sensitive mutant para(bss1) causes behavioral paralysis that resembles paralysis caused by mechanical stimulation, in...

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發表在:Genetics
Main Authors: Saras, Arunesh, Wu, Veronica V., Brawer, Harlan J., Tanouye, Mark A.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560784/
https://ncbi.nlm.nih.gov/pubmed/28630111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.194779
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