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Mutations of the Calcium Channel Gene cacophony Suppress Seizures in Drosophila

Bang sensitive (BS) Drosophila mutants display characteristic seizure-like phenotypes resembling, in some aspects, those of human seizure disorders such as epilepsy. The BS mutant para(bss1), caused by a gain-of-function mutation of the voltage-gated Na(+) channel gene, is extremely seizure-sensitiv...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Saras, Arunesh, Tanouye, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714812/
https://ncbi.nlm.nih.gov/pubmed/26771829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005784
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