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A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques

Despite effective control of plasma viremia with the use of combination antiretroviral therapies (cART), minor cognitive and motor disorders (MCMD) persist as a significant clinical problem in HIV-infected patients. Non-human primate models are therefore required to study mechanisms of disease progr...

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Pubblicato in:PLoS Pathog
Autori principali: Matsuda, Kenta, Riddick, Nadeene E., Lee, Cheri A., Puryear, Sarah B., Wu, Fan, Lafont, Bernard A. P., Whitted, Sonya, Hirsch, Vanessa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560746/
https://ncbi.nlm.nih.gov/pubmed/28787449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006538
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