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Morphologic, phenotypic, and transcriptomic characterization of classically and alternatively activated canine blood-derived macrophages in vitro

Macrophages are a heterogeneous cell population playing a pivotal role in tissue homeostasis and inflammation, and their phenotype strongly depends on the micromilieu. Despite its increasing importance as a translational animal model for human diseases, there is a considerable gap of knowledge with...

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Veröffentlicht in:PLoS One
Hauptverfasser: Heinrich, Franziska, Lehmbecker, Annika, Raddatz, Barbara B., Kegler, Kristel, Tipold, Andrea, Stein, Veronika M., Kalkuhl, Arno, Deschl, Ulrich, Baumgärtner, Wolfgang, Ulrich, Reiner, Spitzbarth, Ingo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560737/
https://ncbi.nlm.nih.gov/pubmed/28817687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183572
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