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Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis

INTRODUCTION: CDV‐DL (Canine distemper virus‐induced demyelinating leukoencephalitis) represents a spontaneously occurring animal model for demyelinating disorders. Axonopathy represents a key pathomechanism in this disease; however, its underlying pathogenesis has not been addressed in detail so fa...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Spitzbarth, Ingo, Lempp, Charlotte, Kegler, Kristel, Ulrich, Reiner, Kalkuhl, Arno, Deschl, Ulrich, Baumgärtner, Wolfgang, Seehusen, Frauke
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4864272/
https://ncbi.nlm.nih.gov/pubmed/27247850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.472
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