RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder

RNA-sequencing (RNA-seq) is a powerful technique to investigate the complexity of gene expression in the human brain. We used RNA-seq to survey the brain transcriptome in high-quality postmortem dorsolateral prefrontal cortex from 11 individuals diagnosed with bipolar disorder (BD) and from 11 age-...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Akula, N, Barb, J, Jiang, X, Wendland, JR, Choi, KH, Sen, SK, Hou, L, Chen, DTW, Laje, G, Johnson, K, Lipska, BK, Kleinman, JE, Corrada-Bravo, H, Detera-Wadleigh, S, Munson, PJ, McMahon, FJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560442/
https://ncbi.nlm.nih.gov/pubmed/24393808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.170
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