טוען...

Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives

Large-scale, deep resequencing may be the next logical step in the genetic investigation of common complex diseases. Because each individual is likely to carry many thousands of variants, the identification of causal alleles requires an efficient strategy to reduce the number of candidate variants....

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מידע ביבליוגרפי
Main Authors: Akula, Nirmala, Detera-Wadleigh, Sevilla, Shugart, Yin Yao, Nalls, Michael, Steele, Jo, McMahon, Francis J
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287916/
https://ncbi.nlm.nih.gov/pubmed/22373213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-5-S9-S76
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