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Detecting Identity by Descent and Homozygosity Mapping in Whole-Exome Sequencing Data

The detection of genetic segments of Identical by Descent (IBD) in Genome-Wide Association Studies has proven successful in pinpointing genetic relatedness between reportedly unrelated individuals and leveraging such regions to shortlist candidate genes. These techniques depend on high-density genot...

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書目詳細資料
Main Authors: Zhuang, Zhong, Gusev, Alexander, Cho, Judy, Pe'er, Itsik
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469503/
https://ncbi.nlm.nih.gov/pubmed/23071825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047618
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