DASH: A Method for Identical-by-Descent Haplotype Mapping Uncovers Association with Recent Variation

Rare variants affecting phenotype pose a unique challenge for human genetics. Although genome-wide association studies have successfully detected many common causal variants, they are underpowered in identifying disease variants that are too rare or population-specific to be imputed from a general r...

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Detalhes bibliográficos
Main Authors: Gusev, Alexander, Kenny, Eimear E., Lowe, Jennifer K., Salit, Jaqueline, Saxena, Richa, Kathiresan, Sekar, Altshuler, David M., Friedman, Jeffrey M., Breslow, Jan L., Pe'er, Itsik
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113343/
https://ncbi.nlm.nih.gov/pubmed/21620352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.04.023
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