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p53-mediated neuronal cell death in ischemic brain injury

p53 is a key modulator of cellular stress responses. It is activated in the ischemic areas of brain, and contributes to neuronal apoptosis. In various stroke models, p53 deficiency or applications of p53 inhibitors can significantly attenuate brain damage. p53-mediated neuronal apoptosis occurs thro...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Hong, Li-Zhi, Zhao, Xiao-Yuan, Zhang, Hui-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560294/
https://ncbi.nlm.nih.gov/pubmed/20502500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-010-1111-0
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