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Aquaporin-4 deficiency attenuates acute lesions but aggravates delayed lesions and microgliosis after cryoinjury to mouse brain

OBJECTIVE: To determine whether aquaporin-4 (AQP4) regulates acute lesions, delayed lesions, and the associated microglial activation after cryoinjury to the brain. METHODS: Brain cryoinjury was applied to AQP4 knockout (KO) and wild-type mice. At 24 h and on days 7 and 14 after cryoinjury, lesion v...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Shi, Wen-Zhen, Zhao, Chun-Zhen, Zhao, Bing, Zheng, Xiao-Liang, Fang, San-Hua, Lu, Yun-Bi, Zhang, Wei-Ping, Chen, Zhong, Wei, Er-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560290/
https://ncbi.nlm.nih.gov/pubmed/22233890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1063-7
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