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Aggravated inflammation and increased expression of cysteinyl leukotriene receptors in the brain after focal cerebral ischemia in AQP4-deficient mice
OBJECTIVE: Aquaporin-4 (AQP4), the main water channel protein in the brain, plays a critical role in water homeostasis and brain edema. Here, we investigated its role in the inflammatory responses after focal cerebral ischemia. METHODS: In AQP4-knockout (KO) and wild-type mice, focal cerebral ischem...
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Publicado no: | Neurosci Bull |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5561818/ https://ncbi.nlm.nih.gov/pubmed/23132680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1281-z |
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