Aggravated inflammation and increased expression of cysteinyl leukotriene receptors in the brain after focal cerebral ischemia in AQP4-deficient mice

OBJECTIVE: Aquaporin-4 (AQP4), the main water channel protein in the brain, plays a critical role in water homeostasis and brain edema. Here, we investigated its role in the inflammatory responses after focal cerebral ischemia. METHODS: In AQP4-knockout (KO) and wild-type mice, focal cerebral ischem...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Shi, Wen-Zhen, Zhao, Chun-Zhen, Zhao, Bing, Shi, Qiao-Juan, Zhang, Li-Hui, Wang, Yan-Fang, Fang, San-Hua, Lu, Yun-Bi, Zhang, Wei-Ping, Wei, Er-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561818/
https://ncbi.nlm.nih.gov/pubmed/23132680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-012-1281-z
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