Silencing of HJURP induces dysregulation of cell cycle and ROS metabolism in bladder cancer cells via PPARγ-SIRT1 feedback loop

Holliday Junction Recognition Protein (HJURP) is a centromeric histone chaperone involving in de novo histone H3 variant CenH3 (CENP-A) recruitment. Our transcriptome and in vivo study revealed that HJURP is significantly upregulated in bladder cancer (BCa) tissues at both mRNA and protein levels. K...

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Vydáno v:J Cancer
Hlavní autoři: Cao, Rui, Wang, Gang, Qian, Kaiyu, Chen, Liang, Qian, Guofeng, Xie, Conghua, Dan, Han C., Jiang, Wei, Wu, Min, Wu, Chin-Lee, Xiao, Yu, Wang, Xinghuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560147/
https://ncbi.nlm.nih.gov/pubmed/28819432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.19967
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