High-efficiency non-mosaic CRISPR-mediated knock-in and indel mutation in F0 Xenopus

The revolution in CRISPR-mediated genome editing has enabled the mutation and insertion of virtually any DNA sequence, particularly in cell culture where selection can be used to recover relatively rare homologous recombination events. The efficient use of this technology in animal models still pres...

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Bibliographic Details
Published in:Development
Main Authors: Aslan, Yetki, Tadjuidje, Emmanuel, Zorn, Aaron M., Cha, Sang-Wook
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Techniques and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560047/
https://ncbi.nlm.nih.gov/pubmed/28694259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.152967
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