Soluble APP functions as a vascular niche signal that controls adult neural stem cell number

The molecular mechanism by which NSC number is controlled in the neurogenic regions of the adult brain is not fully understood but it has been shown that vascular niche signals regulate neural stem cell (NSC) quiescence and growth. Here, we have uncovered a role for soluble amyloid precursor protein...

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Bibliographic Details
Published in:Development
Main Authors: Sato, Yuya, Uchida, Yutaka, Hu, Jingqiong, Young-Pearse, Tracy L., Niikura, Takako, Mukouyama, Yoh-suke
Format: Artigo
Language:Inglês
Published: The Company of Biologists Ltd 2017
Subjects:
Stem Cells and Regeneration
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560038/
https://ncbi.nlm.nih.gov/pubmed/28694255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143370
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